Daniel Eachus started his stand-up comedy career in high school, having never seen a live routine.

Set to perform in his first show in a friend’s backyard for some classmates and neighbors, the Fresno, Calif., native was ready to go — with a 45-minute set.

“I’d only seen like TV stand-up, so when I went to try it, I just thought comedians do like 45 minutes,” he said. But really, first-time stand-ups tend to spend three to five minutes at an open mic.

And while it was long — like, really long — it wasn’t half bad, he said. Even some of his friends’ parents (who had snuck in to watch) were laughing.

“Not only had I made my friends laugh, but to have made these strangers laugh was something,” Eachus said. “I was like, ‘OK, maybe there’s something here.’”

Eachus will headline Loonees Comedy Corner this weekend, with Eeland Stribling and host Luke Gaston also on hand. In his 15-year comedy venture, Eachus has released two stand-up albums, advanced to the finals on Comedy Central’s “Up Next” and has appeared on Fox and Hulu’s “Laughs.”

Since his first routine, he’s completed more than 4,000 shows.

“It’s almost surprising to me that I’ve been doing it that long,” Eachus said.

Like many comedians, Eachus can’t get away from stand-up. Besides the high from laughs, he enjoys the work involved in perfecting the craft, comparing stand-up to a “Rubik’s Cube that fights back.”

“It’s the greatest feeling in the world to get laughs and make people’s nights or days or whatever better. And that feeling is something hard to compare to anything really,” he said. “But I think the thing that keeps a lot of us here, and myself included, is this giant puzzle that’s always changing.”

While his set has changed a lot over the years, he tends to draw from his experiences. His sets are pretty clean — not intentionally so, he admits, he just doesn’t want to limit himself.

“I want to talk about everything,” Eachus said.

Lately, he’s been doing a lot of crowd work at his shows, Eachus said. He hopes that during his shows he can draw the audience into the moment, helping viewers unplug for a little bit.

“Times are constantly changing. The way the world sees itself is constantly changing. Society is always changing. To be able to adapt to all that and still be yourself and still find humor in the world, it’s the puzzle part of it that keeps a lot of us, myself included, doing it for forever,” he said.